Parts of Melbourne's city centre has been reopened after police locked down the area to negotiate with a man carrying petrol cans and hazardous material.
A police critical incident response team was sent to 181 William Street about 7.45am on Tuesday, as officers blocked off the road and negotiated with the man.
The man was arrested and taken to hospital for observation under police guard. Police said the scene had since been declared safe.
Emergency service personnel earlier responded to reports the man was behaving erratically at the building while in possession of hazardous substances.
Fire Rescue Victoria said the incident was declared under control at 8.15am after firefighters determined there was no flammable risk.
Witnesses Sam Di Palma and Daniel Safstrom said they were getting a coffee when they saw a man in the building with a trolley and officers trying to talk to him.
"A bloke (was) behind a counter with a trolley full of chemicals or explosives," Mr Di Palma told AAP.
Mr Safstrom said the police "sent one of their guys in to sit down and negotiate, so they both grabbed a chair".
"I'm a bit shocked to be honest. It's something different," he said.
Another witness, Abraham Elosman, said the incident gave him flashbacks to the Bourke Street Mall attack in January 2017.
"I thought maybe they were doing an exercise or something. I didn't think there was gonna be this big issue," he told AAP.
"But when I saw the shields and the fire brigade come in, I was a bit worried. I thought 'I hope it will be OK'."
The building houses offices for CGU Insurance, the Commonwealth Director of Public Prosecutions, Court Services Victoria and legal firms including Gordon Legal and Baker McKenzie.
