Police have locked down a section of Sauchiehall Street after a 'disturbance' between two men.
Officers are currently outside the Burger King restaurant and have cornered a section of the pavement and road off.
A 27-year-old man has been taken to Queen Elizabeth University Hospital and a 65-year-old man has been taken to Glasgow Royal Infirmary.
Both men sustained serious injuries.
Emergency services are still in attendance and the road remains closed.
A picture seen by Glasgow Live shows officers guarding the cordoned area.
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A spokesperson says enquiries into the incident are ongoing.
A Police Scotland spokesperson said: "Officers were called to a report of a disturbance on Renfield Street, Glasgow, around 4.55pm on Monday, 29 March.
"A 27-year-old man has been taken to Queen Elizabeth University Hospital and a 65-year-old man has been taken to Glasgow Royal Infirmary.
"Both men sustained serious injuries. Officers remain on scene carrying out enquiries into the incident."
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