Theresa May is facing Jeremy Corbyn across the Despatch Box for the last time before Parliament rises for the conference season recess.
Brexit is likely to once again dominate the debate, after the Commons voted to pass the Government's EU Withdrawal Bill.
Mr Corbyn is also likely to ask the Prime Minister about plans for lifting the public sector pay cap next year. It was announced this week that police officers and prison officers will receive a 1 per cent pay rise - a move that received criticism because it is less than the rate of inflation, meaning it is, in effect, a pay cut.
Elsewhere in British politics this week:
Government passes controversial 'power grab' motion allowing it to pass laws without Parliament
Trade union leaders threaten illegal strike over public sector pay cap
Labour secures vote which could embarrass Tories over planned tuition fees hike
Police and prison officers will receive higher pay rise as public sector pay cap is lifted
Merkel ally warns Theresa May's approach to Brexit 'will not work'