Visits to A&E in Nottingham plummeted by almost 50% in April compared to the same month last year.
At the height of the coronavirus pandemic, the accident and emergency department at the Queen's Medical Centre was visited 46% less than the year before.
Concerns have been raised that some illnesses may become worse as people opt to avoid visiting the emergency department for fear of the Covid-19 virus.
But nurses who work at the QMC, which is operated by Nottingham University Hospitals NHS Trust, previously urged people to visit A&E if they think it is an emergency.
Nottinghamshire GP Dr Thilan Bartholomeuz also warned people could lose years of their lives if they ignore signs of cancer.
The trust had planned for the outbreak in the city and has not once been overwhelmed as a result of the virus.
A spokesman for NUH said: "We would like to remind the people of Nottingham that GPs, pharmacies and 111 online services are still available if you need medical help.
"Our emergency department remains open for serious or life-threatening emergencies, please don't be scared or worried about coming to the hospital, especially if it’s an emergency. We are here 24/7."
NUH added that there has been some day to day fluctuation, with an underlying growth of 6% week on week.
