Liverpool Council is set to approve major plans for 650 apartments, a new hotel and shops in the Baltic Triangle.
The proposal from Chaloner Street Developments is for the former Norton's Scrap Metal site, with the homes to be built across three towers ranging between 17 and 27 storeys.
The plans include a large 200-bed hotel as well as retail units, and are for the junction between Chaloner Street, Flint Street and Parliament Street, according to the Local Democracy Reporting service.
Liverpool Council's planning committee will consider the current application, submitted earlier this year, next week. Officers have recommended the plans for approval.
The tallest of the blocks would be around 77m tall, with the other two standing at approximately 53m.
A statement submitted with the application said the developer's aim for the towers is to "build on and enhance" the Baltic's distinctive appearance.
It said: "With a view to delivering a step change in the character and quality of the west side of this key infrastructure routeway, and to create a unique gateway to the thriving Baltic area, the public realm along the development frontage will be entirely renewed with robust, high quality landscape interventions.
"These include cascading steps and ramped approach into the development, external seating and performance areas, public art areas, caf seating and tree and shrub planting all set over a mix of tiered terraces, intended to create the welcoming and defined entrance that the Baltic Triangle deserves."
Nearby businesses Baltic Bakehouse and Camp and Furnace have both raised issues with the plans, calling on the council to make sure there is proper acoustic proofing in the building to limit noise complaints from residents.
They have also called on the developers to mitigate the need for road closures during construction.
Riverside ward councillor Steve Munby has asked the council to request the Section 106 contributions for the development are fully payable with no reductions.
Liverpool Council's planning committee will decide on the proposals next Wednesday.