The New England Patriots have four starting offensive linemen who are trending toward not playing on Sunday in Week 5.

New England placed left tackle Isaiah Wynn and left guard on the COVID-19/reserve list, with one player being a not-fully-vaccinated close contact and the other testing positive. It’s unclear which is which. New England has also seen two more of their starting linemen get downgraded on the injury report this week. Right tackle Trent Brown has missed every game since Week 1, but had been a limited participant. He has not practiced Wednesday or Thursday. Right guard Shaq Mason also didn’t participate with an abdomen injury in either practice so far.

That puts four of the team’s five offensive linemen in an uncertain position as they prepare for the Houston Texans on Sunday.

Patriots' lengthy injury report.

Trent Brown, Shaq Mason did not participate again, putting their status for the game in great uncertainty. LT Isaiah Wynn and LG Michael Onwenu, meanwhile, remain on the COVID-19/reserve list. pic.twitter.com/Gv3DdIQNSN

— Henry McKenna (@McKennAnalysis) October 7, 2021

All four offensive linemen could miss the game. That would leave the team to rebuild a makeshift unit around starting center David Andrews. New England has offensive linemen Ted Karras, Yasir Durant, Justin Herron and Yodny Cajuste.