A number of measles cases have been reported at the Queen's Medical Centre - and Public Health England (PHE) is urging anyone with symptoms to contact their GP.
Four people have presented themselves with measles at Nottingham University Hospitals (NUH) over the last few days.
Two people are currently being treated for the disease at the QMC, and PHE East Midlands says it is working "closely" with the hospital to make sure anyone who could have been exposed is receiving the appropriate follow-up.
Dr Vanessa MacGregor, consultant in communicable disease control at PHE East Midlands, said: "Measles is an unpleasant disease and spreads very easily amongst anyone who has not had two doses of MMR.
"It's never too late to catch up with vaccinations if you or your child is behind.
"If you are unsure if you or your children have had the full two doses of MMR, speak to your GP who will have a record of the vaccinations they have received."
The illness begins with 'cold-like symptoms', PHE added, and can be accompanied by fever and a rash.
A PHE spokeswoman added: "If you think that your child may have measles, please keep them at home and phone your GP or NHS 111 for advice, rather than visiting the surgery or A&E, to prevent the illness spreading further."
Earlier on this month, May, King's Mill Hospital in Sutton-in-Ashfield advised patients and visitors to the Emergency Department to seek advice from their GP if symptoms appeared - following the possibility they could have been exposed to measles.
