A passenger remains in hospital in a serious condition after a collision involving a car van in Runcorn.
Police were called to the exit slip from Daresbury Expressway onto Astmoor Road on Wednesday morning at 7.15am.
The crash involved a Vauxhall Corsa car and a Mercedes Sprinter van.
A Cheshire police spokesman said the Corsa's driver and passenger were taken to hospital while the van driver, a 32-year-old man from Liverpool, was not injured.
The car passenger, a 46-year-old man from Runcorn, remains in hospital in a serious condition.
The driver, a 29-year-old man from Runcorn, has been discharged.
One resident told the ECHO the car's front end was "gone".
Emergency services shut the the slip road and a section of Astmoor Road while an investigation took place.
The collision happened just a few days after a 22-year-old motorist died following a crash on the Southern Expressway in Runcorn on Saturday.
And last month, the heads of Cheshire police, the county's fire service, and the North West Ambulance Service joined forces to sound the alarm over a worrying rise in the number of fatal smashes on Cheshire's roads.
At the time of the campaign Fatal 5 launch on May 9, there had been 23 fatalities on the county's roads in 2019 - a rate of more than one a week and on course to reach around 66 for the year. This would be three times the number who died in 2017, and more than last year's total of 46 fatalities.
A Cheshire police spokeswoman said earlier this week that so far in 2019, there have now been 25 deaths on the county's roads.
The Fatal 5 campaign was named after the five most common causes of collisions, in descending order of frequency: careless driving, driving too fast, influence of drink or drugs, not wearing a seatbelt, and using a mobile phone.
A shocking reel of bad driving was released alongside the campaign launch.
The latest crashes came amid a period of heavy rain and wet road conditions.
Anyone with any information in relation to yesterday's collision in Astmoor, or any dashcam footage of the incident, is urged to call Cheshire police on 101, quoting IML 425919.
Submit dashcam footage online .
