Manchester United's under-23s will take on holders Sunderland in this season's Papa John's Trophy.
Bradford City and Lincoln City also make up the rest of United's group, while Liverpool's under-23s will take on Bolton Wanderers, Port Vale and Rochdale.
Arsenal's youngsters face Swindon, Newport and Plymouth, while Tottenham are up against Oxford, Cambridge and Stevenage.
Chelsea's kids face Exeter, Bristol Rovers and Cheltenham, and Manchester City take on Rotherham United, Doncaster and Scunthorpe.

Sunderland are the current holders of the competition having beaten Tranmere on penalties at Wembley in March, a day after the delayed 2019-20 final when Salford City beat Portsmouth on penalties.
Here are the groups in full:
Northern Groups
Group A
Everton, Carlisle United, Hartlepool United, Morecambe
Group B
Leeds, Oldham Athletic, Tranmere Rovers, Salford City
Group C
Wolves, Wigan Athletic, Crewe Alexandra, Shrewsbury Town
Group D
Liverpool, Port Vale, Rochdale, Bolton Wanderers
Group E
Manchester City, Rotherham United, Doncaster, Scunthorpe
Group F
Manchester United, Bradford, Lincoln, Sunderland
Group G
Leicester, Accrington Stanley, Barrow, Fleetwood
Group H
Newcastle, Sheffield Wednesday, Harrogate, Mansfield

Southern Groups
Group A
West Ham, Colchester, Gillingham, Ipswich
Group B
Crystal Palace, Wimbledon, Portsmouth, Sutton
Group C
Aston Villa, MK Dons, Burton, Wycombe
Group D
Brighton, Forest Green, Northampton, Walsall
Group E
Chelsea, Exeter, Bristol Rovers, Cheltenham
Group F
Arsenal, Swindon, Newport, Plymouth
Group G
Southampton, Crawley, Charlton, Leyton Orient
Group H
Tottenham, Oxford, Cambridge, Stevenage