SAN DIEGO _ With a bunt single, a double and a home run, the San Diego Padres accomplished in a span of seven pitches Tuesday night the jump-start they had been seeking all season.
It led to a 6-3 victory over the Seattle Mariners in the opener of a two-game series at Petco Park.
The first of Franmil Reyes' two homers gave the Padres a 3-0 lead in the second inning, the biggest lead they'd had that early in any of their 24 games.
The Mariners scored twice off Nick Margevicius in the fifth inning, his last one of the night.
A solo homer by Reyes and two-run shot by Austin Hedges made it 6-2 in the sixth. Hedges' homer sailed in and out of Mariners center fielder Mallex Smith's glove and over the wall.
The Padres' biggest offensive output in 10 games began with Wil Myers' bunt to the left side on the first pitch of the second inning. Myers scored on Eric Hosmer's line drive double to right-center field. Reyes followed with his homer to left-center.
It was the first time the Padres scored three runs within the first two innings of a game this season. It was the second game in a row they built a three-run lead in the first three innings, and they are 4-0 in the games in which they have done so this season.
It was a struggle much of the night for Margevicius (2-2), but the rookie allowed just the two runs despite quintupling his previous high with five walks.
Brad Wieck pitched a scoreless sixth. Craig Stammen allowed a run in the seventh. Trey Wingenter was perfect in the eighth, and Kirby Yates was perfect in the ninth to earn his 11th save, tied for the major league lead.
Fernando Tatis Jr. extended his hitting streak to 11 games with a single in the second inning.