Owen Hargreaves criticised Manchester United's attacking quintet during the defeat by Sheffield United at Old Trafford.
Goals from Kean Bryan and Oliver Burke secured victory for Chris Wilder's men - only their second of the Premier League season far.
The result has dented United's unlikely challenge, with their below-par home record continuing under Ole Gunnar Solskjaer.
Solskjaer paid the price for his team selection with Anthony Martial, who was selected at the expense of Edinson Cavani, struggling immensely.
Hargreaves believes United's other creative players Marcus Rashford, Mason Greenwood, Bruno Fernandes and Paul Pogba also disappointed in the defeat while highlighting some major issues at the back too.
"I can't really remember Ramsdale having to make any saves," Hargreaves told Premier League Productions. "They just weren't at it today.
"Offensively or defensively. You think about Rashford, Martial, Greenwood, Pogba and Fernandes - that fabulous front five didn't really create anything.
"Defensively, they were quite vulnerable at times. Even though their form has been fabulous, Solskjaer will be disappointed they just weren't at the races today."
Hargreaves believes United's offensive players also contributed to Sheffield United's second goal, failing to spot the danger and track back to deny the Blades.
He added: "Solskjaer will be furious with the transition initially. I don't think Sheffield United wanted to attack but because the front four didn't want to come back, there was only really two blocks. The Sheffield United players thought, 'wow, there is a chance here'. They joined in slowly.
"Credit to Burke, he's not a goal scorer, he just sat in that pocket of space in between the lines. Telles and Matic swapped positions and that created a tiny bit of confusion.
"Burke is away from Telles, Pogba and Fernandes and they just react a little bit late."
