Ole Gunnar Solskjaer has confirmed two fresh injuries ahead of Manchester United's upcoming FA Cup encounter with Derby County.
Solskjaer revealed that Daniel James and Aaron Wan-Bissaka are both set to miss out at Pride Park.
Wales winger James missed the weekend draw with Everton, but £50million full-back Wan-Bissaka played the entire 90 minutes at Goodison Park.
He will undergo tests on Wednesday on a back problem, but is likely to miss out against the Championship side, admitted Solskjaer.
That will see them join Marcus Rashford and Paul Pogba on the sidelines - although the latter is working towards a return.
Solskjaer said: "Paul [Pogba's] still working with the physios outside and he won’t be training with the first-team until next week and then let’s see how long that will take.
"He will need some time to get his football fitness back.
"[James] will probably miss out on this one as well, Marcus and Paul still out.
"And I think [Wan-Bissaka] might be struggling, got a test today but he struggled in our last game against Everton with his back, so he might be out."
Manchester United will book a place in the quarter-finals should they beat the Rams away from home on Thursday night.
The Red Devils enjoyed a relatively good February, most notably beating Chelsea and Watford in the league.
In the Premier League they currently sit in fifth place, with Wolves level on points but behind on goal difference. County, meanwhile, sit a modest 13th in the Championship.
In January they signed United's all-time record goalscorer Wayne Rooney as a player-coach, and he recently spoke about how he will be conflicted playing against his former side.
“For me it is a big game playing against my former team,” said the former England captain. “They will be favourites.
“I captained Everton against them and it is always strange when you play against a former team, especially when you have been there so long. I love the club and it is a team I want to do well and win.
“But for this 90 minutes I want us to win and to try and go through.
“I have visited Derby as a Manchester United player in the FA Cup before and know what it means to the fans and staff here.
“It is for us as players to go on the pitch to try and get a good result.
