Alex Palou is once again on the top step of the podium, winning at Portland with Felix Rosenqvist second and Will Power third. The margin of victory was 4.1 seconds.
Rinus VeeKay earned another impressive result for Juncos Hollinger in fourth, and Kyle Kirkwood finished fifth.
Rosenqvist led the first 30 laps of the race, with Palou moving ahead through the first sequence of pit stops. Palou took the lead for the final time on Lap 87 of 110 after Power made his stop, and he never looked back.
19 of 25 starters finished on the lead lap, and Marcus Armstrong was the only DNF.
| cla | # | driver | team | laps | time | gap | int | mph | pits | retirement | pts |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 10 |  Alex Palou |
Chip Ganassi Racing | 110 | 1:55'03.4235 | 112.661 | 3 | 53 | |||
| 2 | 60 |  Felix Rosenqvist |
Meyer Shank Racing with Curb-Agajanian | 110 | 1:55'07.5402 | 4.1167 | 4.1167 | 112.593 | 3 | 42 | |
| 3 | 26 |  Will Power |
Andretti Global | 110 | 1:55'11.4860 | 8.0625 | 3.9458 | 112.529 | 3 | 36 | |
| 4 | 76 |  Rinus VeeKay |
Juncos Hollinger Racing | 110 | 1:55'20.0002 | 16.5767 | 8.5142 | 112.391 | 3 | 32 | |
| 5 | 27 |  Kyle Kirkwood |
Andretti Global | 110 | 1:55'22.8018 | 19.3783 | 2.8016 | 112.345 | 3 | 30 | |
| 6 | 28 | Marcus Ericsson |
Andretti Global | 110 | 1:55'23.4556 | 20.0321 | 0.6538 | 112.335 | 3 | 28 | |
| 7 | 3 |  Scott McLaughlin |
Team Penske | 110 | 1:55'24.8476 | 21.4241 | 1.3920 | 112.312 | 3 | 26 | |
| 8 | 2 | Josef Newgarden |
Team Penske | 110 | 1:55'25.5259 | 22.1024 | 0.6783 | 112.301 | 4 | 25 | |
| 9 | 7 |  Christian Lundgaard |
Arrow McLaren | 110 | 1:55'29.1735 | 25.7500 | 3.6476 | 112.242 | 3 | 22 | |
| 10 | 8 |  Kyffin Simpson |
Chip Ganassi Racing | 110 | 1:55'32.7018 | 29.2783 | 3.5283 | 112.185 | 3 | 20 | |
| 11 | 5 |  Patricio O'Ward |
Arrow McLaren | 110 | 1:55'36.5135 | 33.0900 | 3.8117 | 112.123 | 3 | 19 | |
| 12 | 12 | David Malukas |
Team Penske | 110 | 1:55'37.4473 | 34.0238 | 0.9338 | 112.108 | 3 | 18 | |
| 13 | 19 |  Dennis Hauger |
Dale Coyne Racing | 110 | 1:55'45.9732 | 42.5497 | 8.5259 | 111.970 | 3 | 17 | |
| 14 | 9 | Scott Dixon |
Chip Ganassi Racing | 110 | 1:55'46.8733 | 43.4498 | 0.9001 | 111.956 | 3 | 16 | |
| 15 | 45 |  Louis Foster |
Rahal Letterman Lanigan Racing | 110 | 1:55'52.3566 | 48.9331 | 5.4833 | 111.868 | 3 | 15 | |
| 16 | 47 |  Mick Schumacher |
Rahal Letterman Lanigan Racing | 110 | 1:56'02.4307 | 59.0072 | 10.0741 | 111.706 | 3 | 14 | |
| 17 | 18 |  Romain Grosjean |
Dale Coyne Racing | 110 | 1:56'02.5276 | 59.1041 | 0.0969 | 111.704 | 3 | 13 | |
| 18 | 6 | Nolan Siegel |
Arrow McLaren | 110 | 1:56'02.8963 | 59.4728 | 0.3687 | 111.698 | 4 | 12 | |
| 19 | 20 | Alexander Rossi |
Ed Carpenter Racing | 110 | 1:56'04.1300 | 1'00.7065 | 1.2337 | 111.679 | 3 | 11 | |
| 20 | 4 |  Caio Collet |
A.J. Foyt Enterprises | 109 | 1:55'05.8056 | 1 Lap | 1 Lap | 111.598 | 3 | 10 | |
| 21 | 14 | Santino Ferrucci |
A.J. Foyt Enterprises | 109 | 1:55'19.3279 | 1 Lap | 13.5223 | 111.380 | 4 | 9 | |
| 22 | 77 | Ray Robb Sting |
Juncos Hollinger Racing | 109 | 1:55'20.6073 | 1 Lap | 1.2794 | 111.359 | 4 | 8 | |
| 23 | 15 | Graham Rahal |
Rahal Letterman Lanigan Racing | 109 | 1:55'42.2831 | 1 Lap | 21.6758 | 111.012 | 4 | 7 | |
| 24 | 21 | Christian Rasmussen |
Ed Carpenter Racing | 106 | 1:55'35.3663 | 4 Laps | 3 Laps | 108.064 | 3 | 6 | |
| 25 | 66 | Marcus Armstrong |
Meyer Shank Racing with Curb-Agajanian | 33 | 46'50.7670 | 77 Laps | 73 Laps | 83.011 | 1 | Mechanical | 5 |
