There was little correlation between the intensity of adverse reactions after COVID-19 vaccination and the amount of neutralizing antibodies produced in the human body by the vaccine, the National Center for Global Health and Medicine announced Tuesday, citing the results of its research.
While the degree of adverse reactions varies from person to person, according to the research, there is no need to worry about the effectiveness of the vaccine even if there is no pain in the arm or fever.
The center analyzed blood samples taken periodically after vaccination from about 220 medical workers at the Kumamoto General Hospital in Yatsushiro, Kumamoto Prefecture, who received the vaccine manufactured by Pfizer Inc. The center examined the amount of neutralizing antibodies, which prevent the novel coronavirus from infecting the cells.
The results showed that the amount of neutralizing antibodies in the human body was not correlated to the intensity of pain in the arm after inoculation, nor whether the person had fever. The research found women tended to have a higher amount of neutralizing antibodies than men.
According to Hiroaki Mitsuya, director general of the center's Research Institute, the amount of neutralizing antibodies was highest on the seventh day after the second vaccination, and decreased by an average of 42% on the 30th day.
"We need to conduct more research to find out how long the antibodies remain," Mitsuya said.
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