Nigel Farage was left covered in milkshake after the drink was thrown over him during a walkabout in Newcastle.
The Brexit Pary leader was in the north east city when a man appeared to take aim and throw the drink at him.
Mr Farage's suit was left covered by the white milkshake.
He was then led away by security as a person was dragged away by a Police Community Support Officer.
Shortly after the incident, Mr Farage could be heard saying "how did you not stop that?" as his staff ushered him away from the scene.
He later tweeted: "Sadly some remainers have become radicalised, to the extent that normal campaigning is becoming impossible.
"For a civilised democracy to work you need the losers consent, politicians not accepting the referendum result have led us to this."
The politician had just given a short speech at the city's Monument as part of a tour of the country ahead of polling day on Thursday.
Mr Farage has become the latest victim of a protest which has seen other European election candidates such as Ukip's Carl Benjamin and ex-English Defence League leader Tommy Robinson suffer similar attacks.
Last week, police apparently ordered a McDonald's outlet near a Brexit Party campaign rally to stop selling milkshakes and ice cream, the restaurant's staff have said.
Game of Thrones fans spot 'coffee cup-gate' round two - but this time it's a water bottle
