The NFL kicks off Week 16 with three games on Saturday. it begins with the Houston Texans facing the Tampa Bay Buccaneers, followed by a couple of divisional battles with the Bills and Patriots and then the Rams and 49ers.
It is time to make our picks against the spread for these games. All odds come from BetMGM.
Texans (-3.5) at Buccaneers

ATS pick: Texans -3.5
Over/under: OVER 50.5
Bills at Patriots (-6.5)

ATS pick: Bills +6.5
Over/under: UNDER 37.5
Rams at 49ers (-6.5)

ATS pick: Rams +6.5
Over/under: UNDER 45.5
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