Harry Kane and Dele Alli both start for Spurs despite returning from their post-World Cup holiday at the start of the week, with the Magpies have summer signing Kennedy back in their ranks after joining for a second season-long loan.
With Jose Mourinho’s side securing an early victory in the form of a 2-1 win over Leicester City on Friday night, Spurs have an early chance to get off the mark as they travel north for the weekend’s early kick-off.
The match is the first of six games on Saturday, with Chelsea also in action as they take on Huddersfield Town at 3pm. The rest of the action sees Bournemouth face Cardiff City, Fulham host Crystal Palace and Watford entertain Brighton and Hove Albion, before Wolves and Everton face-off in the day’s late game.
Right that's the team news sorted...excited to have four games to follow as the Premier League comes back with a bang? We'll have all the goals, cards and key moments if you're struggling to keep tabs on all the games at once.
Plenty to play for today with two of the Premier League new boys kicking off at 3pm, and returning clubs assessing how their new signings will settle in.
Game one is over, and positive signs for both sides - Spurs picking up an important win as they recover from World Cup exploits, but Newcastle put up a good fight and will feel unlucky to end up with nothing from the game.
Plenty of 3pm kick offs to come in around 30 minutes, here's the fixtures we'll be keeping an eye on
An important victory for Spurs as they continue to recover from a World Cup that featured plenty of their players. Jan Vertonghen with the scrappy opener, Joselu equalised for Newcastle, before Dele got the winner in a frantic first half. Chances for both sides in the second, with Newcastle striking the bar twice, and a late injury scare for DeAndre Yedlin, as the Magpies ended the game with 10 men.
88 mins: Harry Kane was almost replaced by Llorente, but instead Dier is down stretching possibly with some cramp, and Pochettino chooses to bring on Amos instead for the closing moments
84 mins: A half chance for Newcastle, but Atsu threads the ball through to Rondon too early as the striker is caught between pulling to the left or right. Rondon will need a couple of games to gel with his new teammates.
As I write that, he hits the post! Shelvey with a brilliant ball forward, Rondon shoots it takes a deflection and strikes the crossbar. Spurs breathe again
82 mins: Into the last ten minutes here, and Rondon hasn't managed to have much of an impact. A corner a couple of seconds ago was almost uncontested as Lloris punched clear, and you feel Newcastle may be running out of time
76 mins: Shelvey at his very best there. Picked out an inch perfect cross field pass for Yedlin, and Lloris flew out of his goal to block it and clear his lines. There is room for Newcastle if they can get the ball out wide
72 mins: As the subs settle in to this one, we have a brief lull in play. Newcastle need Rondon to put his stamp on this game, but hasn't had much service so far
60 mins: Goalmouth scramble! Hugo Lloris somehow stops Newcastle getting the equaliser after chaos in the box from a corner. Perez going the closest, but Lloris keeps him out
