Warning signs featuring a silhouette of a hedgehog will appear on roadsides to advise drivers of the potential hazards to small wildlife.
They will be situated in areas where there are large numbers of hedgehogs, and other small animals like otters, squirrels and badgers.
The Department for Transport says it hopes the signs will help reverse a decline in wildlife numbers and prevent accidents.
Transport Secretary Chris Grayling urged animal welfare groups and local councils to help identify accident and wildlife hotspots where the new signs should be located.
Latest estimates put the hedgehog population in England, Wales and Scotland at about one million, compared with 30 million in the 1950s, the BBC reports.
The DfT says its new sign is "filling a gap" between the existing signs carrying warnings about smaller animals such as migratory toads and wildfowl, and those highlighting larger animals.
Jill Nelson, from the People's Trust for Endangered Species (PTES), says the signs were created after the charity and the British Hedgehog Preservation Society (BHPS) discussed their concerns with Mr Grayling.
"We welcome this focus on road safety and protection for all small mammals," she said.
Research by PTES and the BHPS in 2018 suggested hedgehogs are disappearing more rapidly in the countryside, as hedgerows and field margins are lost to intensive farming, and the DfT says the sign is designed to reverse their decline "in particular".
The DfT says that between 2005 and 2017,100 people were killed, and a further 14,173 injured in accidents in Britain where an animal, excluding horses, were in the road.
