The NFL schedule was released last week and so did some early betting lines.
The Chargers begin their run toward the Super Bowl in front of their home crowd, opening the year against the Colts.
Vegas sees Los Angeles as the favorites right now with the Westgate Superbook making them 3.5-point favorites in early Week 1 odds that were released last week.
The last time these two teams met was in 2016. The Colts defeated the Chargers by the score of 26-22.
Playing at home should give L.A. the slight advantage, but the Colts are no slouch of a team anymore. Indianapolis earned a trip to the playoffs last season, but came up short against the Chiefs in the AFC Divisional Round.
Quarterback Andrew Luck appeared to play at a high level and the Colts added some valuable pieces, including the 2018 Defensive Rookie of the Year, linebacker Darius Leonard.
The over/under is set at 48 points, which is fair. The matchup features two of the leagues best quarterbacks, but it should come down to a battle of defenses when all is said and done.
