There have been more than 4,000 new positive coronavirus tests recorded in the last 24 hours, with the number of deaths increasing by 13.
This was more than 1,500 fewer than Sunday's figures, when more than 5,500 people in the UK were diagnosed with coronavirus in 24 hours and 18 deaths were recorded.
It is the first time in weeks that the upward trend has reversed.
The government said that, as of 9am on Monday, there had been a further 4,044 lab-confirmed cases of coronavirus in the UK, taking the overall number of cases confirmed to 439,013.
The government also said a further 13 people had died within 28 days of testing positive for Covid-19 as of Monday.
This brings the UK total to 42,001.
Separate figures published by the UK’s statistics agencies show there have now been 57,600 deaths registered in the UK where Covid-19 was mentioned on the death certificate.
Daily data is not available on hospital admissions. But figures - last updated on Friday - reveal that there are now 262 patients on ventilation.
Separate data released today showed that Knowsley currently has the highest weekly rate of new cases of Covid-19 in England.
A total of 422 cases were recorded in Knowsley in the seven days to September 25 – the equivalent of 279.7 cases per 100,000, up sharply from 152.5 in the previous week (the seven days to September 18).
Eight other areas of England now have weekly rates above 200 cases per 100,000 people, including Liverpool where the rate has jumped from 165.4 to 262.2 with 1,306 new cases recorded.
More than 1,600 new cases of Covid-19 were recorded in Birmingham in the seven days to September 25.
A total of 1,657 new cases were recorded – the equivalent of 145.1 per 100,000 people, up from 96.2 in the previous week.
Other cities continuing to see increases in their weekly rate include Newcastle upon Tyne (up from 111.6 to 238.1, with 721 new cases); Manchester (up from 140.7 to 207.3, with 1,146 new cases); and Salford (up from 125.9 to 156.9, with 406 new cases).
All figures are based on Public Health England data published on Monday.
