Arsenal manager Mikel Arteta says he could be without Kieran Tierney and Alexandre Lacazette for the Europa League semi-final second leg against Villarreal next week.
Tierney has missed Arsenal's last six games with a knee injury, but wasn't deemed fit enough to be named in the squad for the Gunners' Premier League clash away at Newcastle on Sunday.
While Lacazette has been missing since the 1-1 draw with Fulham last month, having not fully recovered from a hamstring injury.
"They haven't trained with us yet," Arteta told Sky Sports ahead of the Newcastle match.
"So it's unlikely to have them ready in the next few games."
The Spaniard made eight changes for Arsenal's league encounter at St James' Park, with David Luiz and Pierre-Emerick Aubameyang both making their returns from injury and illness respectively.
"It was just to prepare today's game in the best possible way," said Arteta when asked why he made so many changes.
"We played 40 minutes [against Villarreal] with ten men, we had a crazy schedule with players who didn't recover. Last week we learned a lesson with Laca... we need fresh players as well."
After the Europa League semi-final Arteta's side face Premier League matches against West Brom, Chelsea and Crystal Palace, before finishing the league campaign with a home game against Brighton on May 23.
