DETROIT _ Rookie right-hander Michael Fulmer allowed a career-high six earned runs against the Red Sox.
The Boston Red Sox got to Fulmer early, hitting a pair of two-run home runs in the first.
The Detroit Tigers went on to lose, 10-2, to the Red Sox on Friday night at Comerica Park.
It was the most runs allowed by the Tigers since a 12-1 loss to the Indians in Cleveland on July 5.
With a day off coming on Monday, Tigers manager Brad Ausmus said before Friday's game that Fulmer's next start would be pushed back by more than one day.
Fulmer allowed 10 hits over 5 2/3 innings with one walk and one strikeout for the Tigers.
David Ortiz hit his 28th home run of the season to give the Red Sox a 2-0 lead. Jackie Bradley Jr. added his 21th home run of the season to give the Red Sox a four-run cushion in the first.
It was the second time Fulmer has allowed five earned runs or more in a game. He gave up five earned runs in a 9-4 loss to the Indians in Cleveland on May 5 in his second career start.
It was the third time this season that Fulmer has allowed four runs in an inning and last since July 22 at Chicago. The White Sox scored four runs in the fifth inning, but the Tigers came back to win the game, 7-5.
Fulmer allowed four runs in the first inning of a 9-4 loss to the Indians on May 5 in Cleveland.
With two outs in the sixth, Fulmer gave up four consecutive singles. RBI singles to Andrew Benintendi and Dustin Pedroia pushed the lead to 6-2 for the Red Sox.
Bruce Rondon gave up a two-run double to Hanley Ramirez in the seventh, which gave the Red Sox an 8-2 lead.
Mark Lowe gave up a two-run double with the bases loaded and one out to Ramirez in the eighth as the Red Sox took a 10-2 lead.
Ramirez finished 3-for-5 with four RBIs for the Red Sox.
Ex-Tiger Rick Porcello improved to 17-3. He allowed two runs (one earned) on four hits over seven innings. He walked two and struck out eight.
The Tigers cut the deficit to 4-2 with a two-run home run by J.D. Martinez in the second inning. It was the 17th home run of the season for Martinez and extended his hitting streak to a season-high 10 games. He finished 2-for-3 with a walk.
Casey McGehee had a walk in the first and single in the fourth and Jarrod Saltalamacchia had an infield single in the seventh.
