Matt Hancock has promised a technological "transformation" of the NHS as he proposed giving patients barcodes and ordering hospitals to do away with paper prescriptions.
The new health secretary, who took over from Jeremy Hunt last week, will use a speech to health professionals to tell them "a tech transformation is coming."
He will also attempt to repair relations with NHS staff, who had an often strained relationship with his predecessor following disputes over junior doctor's pay and other matters.
Mr Hancock used his previous role as culture secretary to focus on harnessing the potential of technology - famously even creating his own "Matt Hancock" app for constituents.
In a speech at West Suffolk Hospital - his first as health secretary - he is expected to outline his plan for boosting technological innovation in the NHS.
He said: "In all my experience the small part is finding or inventing the technology. The big part is embedding a culture of always looking for the best possible technology and embracing it.
"I want to drive that culture change, and I want to work with everyone across the NHS and social care system to embrace the next generation of technology.
He added: "From today let this be clear: tech transformation is coming.
"The opportunities of new technology, done right across the whole of health and social care, are vast. Let’s work together to seize them.’"
He is expected to praise the Scan4Safety scheme, which sees patients given a barcode so they can be easily tracked and monitored by staff. A similar system is used to manage medical supplies and equipment. He also urged hospitals to move away from paper prescriptions and upgrade computers systems in order to improve patients safety and care.
The health secretary will say £412m will be invested in helping hospitals improve their use of technology,while a further £75m will be available for upgrading computer systems in order to save money and cut potentially lethal medication errors.
Mr Hancock will also use the speech to attempt to rebuild relations between the government and NHS staff, describing low morale among employees as "heart-breaking".
He will say: "The nation’s health is determined by the health of the health and care workforce, so it is heart-breaking to see how undervalued you often feel.
"The sense of duty and public service that motivates you to go into health and care is one of the things that make the NHS the institution it is.
Pitching himself as a staunch ally of NHS workers, he will add: "I am determined that the commitment you show to your patients is matched by the commitment we show to you.
"So I have a clear message: I value you. I admire you. I will fight for you and I will champion you."
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As part of plans to improve conditions for NHS staff, Mr Hancock will announce a consultation on issues facing employees, including bullying and harrasment, workforce diversity, training and career progression.
He will tell staff: ‘‘‘I want to ensure training is organised and funded so that everyone can reach their full potential.
You know better than me the pace at which modern medicine moves and so it’s crucial that your training looks to incorporate new technology that can save you time and offer better care.’
Mr Hancock will also say NHS leaders must do more to reflect the diversity of the workforce - highlighting that only five chief executives comes from a BAME background. 12 per cent of NHS staff feel they are discriminated against, he said - a figure that rises to 24 per cent for people from ethnic minorities.
"People cannot be expected to deliver world class care when facing bullying and harassment on this scale," he will say.
