Queensland's COVID-19 vaccine rollout is set to begin, with 100 frontline health workers on the Gold Coast to receive the state's first jabs.
And the state's chief health officer says remaining restrictions on residents are likely to change as a critical mass of people become vaccinated.
Workers at the Gold Coast University Hospital will receive their first Pifzer vaccine on Monday, followed later in the week by workers at Brisbane's Princess Alexandra Hospital and then workers in Cairns.
About 1000 people would be vaccinated in the first week of the rollout.
Premier Annastacia Palaszczuk said the first phase of the vaccine rollout in Queensland would cover about 125,000 people - about 37,000 in the hotel quarantine system and 88,000 in care settings.
The next phase would include one million Queenslanders including those aged over 70, all healthcare workers, Indigenous Australians aged over 55, Queenslanders with a disability and emergency service teams.
All adult Queenslanders will be vaccinated by the end of October and Ms Palaszczuk implored her state's residents to remain patient.
"This is to ensure that we get the vaccine out to where it's needed the most, our frontline hotel quarantine workers and for the Commonwealth, aged care workers and residents," Ms Palaszczuk told reporters on Sunday.
"We'll be keeping you updated every step of the way so there's no need to panic - we don't have any community transmission in Queensland."
Six hubs in north and south Brisbane, the Gold Coast, Sunshine Coast, Townsville and Cairns will administer the vaccine.
All COVID-19 vaccines are free to all people in Queensland.
Chief health officer Jeannette Young told reporters that Monday would mark an "extremely exciting" day that warranted celebration around Queensland.
Dr Young reiterated a second vaccine shot would be required 21 days after the first for the Pfizer jab, or 12 weeks later for the AstraZeneca vaccine.
"It's clear this vaccine will stop you getting severe disease and dying and that's what we want from a vaccine, the first thing we want," Dr Young said.
Dr Young said that once a critical mass of Queenslanders had received the vaccination, remaining restrictions would likely change.
"It won't change anything tomorrow morning of course, but as we get more people vaccinated, it will change how we manage things."
Ms Palaszczuk also said talks were continuing with the federal government on a purpose-built quarantine camp near Toowoomba.
