Pablo Mari starts in the Arsenal defence against West Ham on Sunday afternoon.
The Spanish defender slots in at centre back alongside David Luiz, whilst there is a surprise start for Calum Chambers at right-back.
Kieran Tierney continues at left-back, while the partnership of Granit Xhaka and Thomas Partey in midfield is restored.
Bukayo Saka has been passed fit for the match at London Stadium and comes into the starting XI, with Martin Odegaard in the no.10 role.
In attack Pierre-Emerick Aubameyang returns to the starting XI after being benched for the north London derby due to breaking club protocol.
He's joined by Alexandre Lacazette who scored the winning goal from the spot against Spurs last week.
There is no place for Hector Bellerin in the starting line-up and football.london understands that the Spanish defender is not carrying any injury.
Arsenal XI: Leno, Chambers, Luiz, Mari, Tierney, Partey, Xhaka, Saka, Odegaard, Aubameyang, Lacazette
Subs: Ryan, Cedric, Holding, Gabriel, Elneny, Ceballos, Smith Rowe, Pepe, Martinelli
