Marcus Rashford was forced off with an injury in Manchester United's clash with West Ham - causing huge problems up front for the Red Devils.
Ole Gunnar Solksjaer is currently without Anthony Martial, while Europa League hero Mason Greenwood is out of action with the flu.
Rashford was named in the United squad to lead the line against West Ham.
But he pulled up with an injury on the hour mark and was forced to make way for Jesse Lingard, who is a winger by trade.
This leaves United, who have been goal shy in recent weeks, without a forward and in a potentially worrying situation.
Reacting to the injury Nevile said on Sky Sports: "You think of the money United have spent. £900m nearly. That's a hell of a lot of money to have any centre forwards."
Manchester United have managed only eight goals in five games so far this season while the likes of Liverpool and Manchester City have netted 11 and 18 respectively.
