Marco Rubio is set to win the Puerto Rico primary.
With a quarter of the votes counted, Rubio received nearly 75 per cent of votes in the US territory, the Associated Press reports.
“The numbers are overwhelming,” Jenniffer Gonzalez, chairwoman of Puerto Rico's Republican Party, told the news agency. “This primary in Puerto Rico... will demonstrate that the Hispanic vote is important.”
If Rubio manages to gain 50 per cent of the vote, he will take home all 23 delegates from Puerto Rico.
The Florida senator now has one territory and one state under his belt. He also won Minnesota’s caucus on Super Tuesday.
Rivals Donald Trump and Ted Cruz had previously called on Rubio to drop out of the four-man GOP race.
Rubio was the only Republican candidate to campaign in Puerto Rico. Voters in the US territory are not able to vote in presidential elections but they do participate in each party’s nominating process.