Tasmania is making coronavirus vaccines mandatory for all public and private healthcare workers.
From October 31 staff will be required to have at least one dose or have evidence of a vaccination booking.
The state government will make a public health directive once the definition of healthcare worker is finalised next week.
"This is a critical step and one that we do not take lightly," Acting Premier Jeremy Rockliff said on Friday.
"However, it is paramount to ensure the protection of our health workforce and the protection of vulnerable patients in their care.
"What we have seen and witnessed in NSW is the devastating impact the virus can have in our healthcare sectors and we must act now."
Quarantine workers will also have to be vaccinated from September 17.
"Healthcare workers, when covid is circulating in the community, are the people more likely to be exposed," Public Health Director Mark Veitch said
Close to 44 per cent of eligible Tasmanians are fully vaccinated, while 60 per cent have had their first dose.
Tasmania, which had 13 virus deaths at the beginning of the pandemic, has recorded just one case this year, a NSW traveller who tested positive while in hotel quarantine.
