David de Gea
Could do nothing about Stuart Armstrong's goal and was denied a clean sheet on his 400th appearance but made a fabulous save from Nathan Redmond yet did not come for the late corner. 6
Aaron Wan-Bissaka
Has to be a contender for a rest at Crystal Palace on Thursday after a fatigued performance. Never got going at either end. 5
Victor Lindelof
Uncomfortable against Southampton's intense pressing initially but improved after the pause and made a vital interception. But lost Michael Obafemi. 6
Harry Maguire
Had to be instructed to get vocal with teammates but was at his most scathing with the referee. Made a key late tackle in the first-half. 6
Luke Shaw
Embarked on a burst that found Marcus Rashford but the forward was flagged offside. Shaw was the most adventurous of the United defenders. 6
Nemanja Matic
Like Wan-Bissaka, might get a breather at Selhurst Park. Often overwhelmed by Southampton's intensity. 5
Paul Pogba
Robbed of the ball by Danny Ings and it led to Southampton's opener. Caught out in possession again soon after. His weakest performance since the restart. Substituted. 4
Bruno Fernandes
So below-par two deliveries in almost as many seconds failed to beat the first man. Still got an assist for Martial's strike. 5
Mason Greenwood
Uncharacteristically quiet against Ryan Bertrand and crudely fouled by Oriol Romeu, who somehow avoided a red card. 5
Marcus Rashford
Took his offside goal well and then moved into the channel to tidily finish Anthony Martial's lay-off. Should have buried a great chance. 7
Anthony Martial
Squandered a one-on-one at 0-0 but atoned with an assist and another stunning goal and embarked on a virtuoso second-half run. 8
Subs
Fred
Offered energy. 6
Brandon Williams
Defended stoutly but forced off injured. 6
Scott McTominay
Offered the defence protection. 5
Daniel James
Forlorn. 4