Liverpool are to be without Alisson Becker for a period of around six weeks, taking the Reds up to the next international break in mid-November.
Inside that period, Liverpool will play seven matches in all - three in the Champions League, against Ajax, FC Midtjylland and Atalanta, and four in the Premier League, against Everton, Sheffield United, West Ham and Manchester City.
Adrian is set to deputise in those games, unless he is injured, with no new goalkeeper to be brought to Liverpool, despite links to Jack Butland at Stoke City.
That is a cause for concern for some, as Josh Williams said on the Analysing Anfield podcast: "When you sign a back-up goalkeeper, you expect your primary goalkeeper to play in the major competitions, but this is not the case at the minute.
"Adrian played between 1000 and 1500 minutes in the Premier League and the Champions League and that is not ideal - you’re leaving yourself open a little bit to the element of chance.
"Liverpool might keep the shots against down to five or six, but if those shots are going against Adrian, there is a risk he will concede them.
"It has got to the point where Liverpool could concede a completely legitimate goal, and rather than think ‘fair enough’, you’re overly keen to look at Adrian.
"You start to think ‘could he have done better there?’, even if he couldn’t have, and it was how I thought with Simon Mignolet and with Loris Karius - Adrian is now in the same bracket."
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At Manchester United, Ole Gunnar Solskjaer has always had David de Gea as his number one option, with Sergio Romero as back-up.
This season, Dean Henderson, who spent last year on loan at Sheffield United, has been added to the mix.
Michael Edwards and Liverpool's recruitment team would never have imagined that Alisson would be missing for a period of three months or so last season, and then another six weeks or so this.
But had that happened at Manchester United, they would have been able to deal with the situation a little better.
Adrian's contract expires at the end of the season, but Liverpool have an option inserted into the deal to extend it by another season should they wish.
There, quite possibly, though, is a decision to be made on whether an upgrade is required.
