Manchester United defenders Axel Tuanzebe and Phil Jones will miss the restart of the Premier League season through injury.
United manager Ole Gunnar Solskjaer confirmed Tuanzebe and Jones are unavailable for the trip to Tottenham on Friday night but Paul Pogba and Marcus Rashford are back from long-term injuries.
Pogba could make his first appearance in 176 days and first start in 263 days now he has recovered from ankle surgery and Marcus Rashford is available again after a back injury.
"We have two players, it's Phil Jones and Axel will probably miss this game and the start," Solskjaer said. "Let's see how bad they are. Apart from that, the rest of the squad is fit and available.
"If selected, of course, Marcus and Paul have been out for a long, long period, but they're available. How long they're going to play for, let's see."
United beat Tottenham in the reverse fixture six months ago 2-1 and triumphed 1-0 at Tottenham in the breakthrough victory for Solskjaer's caretaker reign last year.
Jose Mourinho suffered his first defeat as Spurs manager at Old Trafford in December but will have Harry Kane, Son Henung-min and Steven Bergwijn back from long-term injuries.
"It's a great game," Solskjaer said. "A big game against one of the best teams in the league, Champions League finalists less than a year ago, a hard game.
"We prepared as well as we can, we've had a couple of in-house 11 v 11s and one 11 v 11 vs West Brom, which will hopefully stand us in good stead.
"We're young, they look fit and ready, and we'll see tomorrow night."
