The road to Gdansk will start in the group stages for Man United as Solskjaer's men search for Champions League qualification this season.
The club will want Champions League football next season as the main goal for this year and have two chances of achieving this - finish in the top four or win the Europa League.
United won the competition for the first time in the 2016/17 season under Jose Mourinho after seeing off Ajax in Stockholm.
Paul Pogba and Henrikh Mkhitaryan found the net which helped the Red Devils qualify for the following season's Champions League.
Will they be able to emulate their Europa League success three years ago as they face trips to the Netherlands, Kazakhstan and Serbia?
Here thepools.com have compiled a preview of all the latest happenings in this year's competition:
Manchester United
Location: Manchester, England
Stadium: Old Trafford
Capacity: 74,879
Manager: Ole Gunnar Solskjaer
Key player: Marcus Rashford
Club coefficient:
Odds to win group: 1/4
Odds to win Europa League: 4/1
AZ Alkmaar
Location: Alkmaar, Netherlands
Stadium: AFAS Stadion
Capacity: 17,023
Manager: Arne Slot
Key player: Oussama Idrissi
Club coefficient: 112th
Odds to win group: 9/2
Odds to win Europa League: 150/1
Road to Group Stage: Qualified for the second qualifying round after finishing 4th in the Eredivisie
Second Round: Hacken (H) 0-0; Hacken (A) 3-0 (won 3-0 on aggregate)
Third Round: FK Mariupol (A) 0-0; FK Mariupol (H) 4-0 (won 4-0 on aggregate)
Qualifying Round: Royal Antwerp (H) 1-1; Royal Antwerp (A) 1-4 aet (won 5-2 on aggregate)
Partizan
Location: Belgrade, Serbia
Stadium: Partizan Stadium
Capacity: 32,710
Manager: Savo Milošević
Key player: Seydouba Soumah
Club coefficient: 81st
Odds to win group: 10/1
Odds to win Europa League: 500/1
Road to Group Stage: Qualified for the second qualifying round after finishing 3rd in the Serbian SuperLiga
Second Round: Connah's Quay (A) 0-1; Connah's Quay (H) 3-0 (won 4-0 on aggregate)
Third Round: Yeni Malatyaspor (H) 3-1; Yeni Malatyaspor (A) 1-0 (won 3-2 on aggregate)
Qualifying Round: Molde FK (H) 2-1; Molde FK (A) 1-1 (won 3-2 on aggregate)
Astana
Stadium: Astana Arena
Capacity: 30,000
Manager: Roman Grygorchuk
Key player: Marin Tomasov
Club coefficient: 51st
Odds to win group: 22/1
Odds to win Europa League: 500/1
Road to the Group Stage: Qualified to the first qualifying round in the Champions League as Kazakhstan Premier League champions
First Round UEFA Champions League Qualifying: CFR Cluj (H) 1-0; CFR Cluj (A) 3-1 (lost 3-2 on aggregate and went to the Europa League qualifying stages)
Second Round: FC Santa Coloma (A) 0-0; FC Santa Coloma (H) 4-1 (won 4-1 on aggregate)
Third Round: Valletta (H) 5-1; Valletta (A) 0-4 (won 9-1 on aggregate)
Qualifying Round: BATE Borisov (H) 3-0; BATE Borisov (A) 2-0 (won 3-2 on aggregate)
Fixtures
Astana (H) - September 19 @ 8pm
AZ Alkmaar (A) - October 3 @ 5.55pm
Partizan (A) - October 24 @ 5.55pm
Partizan (H) - November 7 @ 8pm
Astana (A) - November 28 @ 3.50pm (yes really!)
