Manchester Crown Court will remain closed 'until further notice' after court and security staff tested positive for coronavirus.
Two members of HMCTS staff, and two members of security, who work at the Spinningfields court have contracted the virus.
Another two people, whose role within the court has not been identified, have also tested positive.
The court building was forced to close for a deep clean last Thursday (August 6) morning, but reopened later that afternoon.
But on Monday, the court had to shut again, after further number of people tested positive for the virus over the weekend. All have provided details of their close contacts.
An update to barristers provided by the Northern Circuit on Monday night said the court was awaiting advice from Public Health England.
Lisa Roberts QC said Crown Square Crown Court would remain closed until it was deemed safe and appropriate for staff to return.
"I have just spoken to our Presider, Mr Justice Dove. He and HMCTS have been in close discussion all day," Ms Roberts said.
"They have been liaising with PHE who are fully aware of the situation. PHE will provide advice as to what next steps should be taken and by whom."
The advice from Public Health is expected to be delivered to senior court staff today (Tuesday). The court is expected to reopen when bosses have the right number of staff on site.
Ms Roberts said of those who had tested positive for Covid-19, two are court staff, and two are security staff.
"These are in addition to the individual who tested positive last week," she added.
"I do not know where these people have been deployed within the building or with whom they have, or are likely to have, come into contact."
Ms Roberts said as much Crown Square work as possible will be accommodated at neighbouring Minshull Street, Bolton Crown Court, or remotely.
A HM Courts and Tribunals Service spokesperson said: “Manchester Crown Court has been deep cleaned in line with public health guidance but will remain closed this week while a number of staff and contractors self-isolate.
“Urgent work will move to nearby Minshull Street.”
