Can a Wolves team which has just returned from a testing Europa League trip to Istanbul upset Pep Guardiola's juggernaut?
We asked the Manchester Evening News' Man City correspondent Stuart Brennan for his verdict.
Unsurprisingly he's upbeat.
Win, lose or draw?
Wolves have given City problems in the last two seasons but they are struggling in this campaign and should be a straightforward three points. As odds of 2/15 with thepools.com suggest. if you are tempted to go for a Norwich style upset - and we're not - you can get a massive 20/1 .
Who's a good bet for 1st scorer?
There are rumours that Phil Foden will start - and he always looks lively and dangerous early in games. He's also a good price, 17/2 to score first and 5/2 any time .
Who's on pens?
Sergio Aguero is likely to start, so he will grab any spot kicks, hence a 6/10 any time scorer price, but 5/2 first goal is solid.
Will City keep a clean sheet?
City protect their defensive vulnerability by keeping the ball and attacking, and that should prove effective against Wolves. Both teams To Score 'No' is 4/7 .