After a convincing win away at Shakhtar Donetsk, City play host to Croatian champions Dinamo Zagreb.
Pep Guardiola's side are favourites to win the competition with thepools.com offering 10/3 and are expected to walkover the group stage and finish top at 1/33 so it is no surprise that City are 1/12 favourites to beat Zagreb.
Key player Raheem Sterling is tipped to be rested as Guardiola rotates his side throughout the season and with the Premier League champions expecting an even tougher challenge against Liverpool, Pep needs to experiment with the squad at the right times.
Here is the latest on Man City's European journey from thepools.com:
Manchester City
Location: Manchester, England
Stadium: Etihad Stadium
Capacity: 55,017
Manager: Pep Guardiola
Key player: Raheem Sterling
Captain: David Silva
Club coefficient: 6th
Odds to win group: 1/33
Odds to win Champions League: 10/3
Road to Group Stage: Qualified automatically as Premier League champions
Shakhtar Donetsk

Location: Donetsk, Ukraine
Stadium: OSK Metalist
Capacity: 38,685
Manager: Luis Castro
Key player: Junior Moraes
Club coefficient: 17th
Odds to win group: 22/1
Odds to win Champions League: 250/1
Road to Group Stage: Qualified automatically as Ukrainian Premier League champions
Dinamo Zagreb
Location: Zagreb, Croatia
Stadium: Maksimir
Capacity: 35,123
Manager: Nenad Bjelica
Key player: Mislav Orsic
Club coefficient: 45th
Odds to win group: 25/1
Odds to win Champions League: 250/1
Road to Group Stage: Qualified to the second qualifying round as Croatian First Football League champions
Second round: Saburtalo (A) 0-2; Saburtalo (H) 3-0 (won 5-0 on aggregate)
Third round: Ferencvaros (H) 1-1; Ferencvaros (A) 0-4 (won 5-1 on aggregate)
Qualifying round: Rosenborg (H) 2-0; Rosenborg (A) 1-1 (won 3-1 on aggregate)
Atalanta

Location: Bergamo, Italy
Stadium: San Siro
Capacity: 80,018
Manager: Gian Piero Gasperini
Key player: Duvan Zapata
Club coefficient: 73rd
Odds to win group: 14/1
Odds to win Champions League:
Road to Group Stage: Qualified automatically after finishing 3rd in Serie A
Results
Shakhtar Donetsk (A) - Wednesday September 18 - 8pm - (W) - 3-0
Fixtures
Dinamo Zagreb (H) - Tuesday October 1 - 8pm
Atalanta (H) - Tuesday October 22 - 8pm
Atalanta (A) - Wednesday November 6 - 8pm
Shakhtar Donetsk (H) - Tuesday November 26 - 8pm
Dinamo Zagreb (A) - Wednesday December 11 - 5.55pm