Stoke City boss Michael O'Neill has tested positive for the coronavirus.
The Northern Irishman's positive test emerged shortly before Stoke were due to play Manchester United in a friendly, report Stoke-on-Trent Live.
That game was subsequently called off, with the manager going into self-isolation for at least a week.
The news is a blow to how Leeds United's Championship rivals will prepare for their first game back following the coronavirus shutdown, which is due to be away to Reading on June 20.
There will also be an increased focus on the results of Stoke City's next round of testing to make sure the infection has not spread throughout the squad.
A statement from the club said: "Stoke City can confirm that manager Michael O’Neill has tested positive for the Covid-19 virus following the latest round of testing on Monday (June 8).
"O'Neill had tested negative in the previous five rounds of testing.
"He will now follow the relevant guidance and undergo a period of isolation, whilst continuing to be in regular virtual contact with his coaching staff and players.
"Assistant manager Billy McKinlay will take charge of training as the Potters prepare for their game against Reading on June 20.
"The Club will be making no further comment on this matter."