Luke Shaw is available for Manchester United's derby clash with Manchester City.
Shaw has missed United's last three games with domestic and European bans but will come back into contention.
Phil Jones is a doubt after hobbling off in Sunday's 4-0 defeat at Everton but Ander Herrera, Eric Bailly and Antonio Valencia are pushing to be available.
Meanwhile, Manchester City are without midfielder Kevin De Bruyne for Wednesday's trip to Old Trafford.
The Belgium playmaker suffered a hamstring injury in Saturday's victory over Tottenham.
De Bruyne could feature again this season but Guardiola admits he is unsure when he will be fit again.
Asked on Tuesday when he might return, Guardiola said: "I don't know, we will see. It is a muscular problem and we will see in the next days but [on Wednesday] he is not available."
Goalkeeper Claudio Bravo (Achilles) remains a long-term casualty but City have no other fitness concerns.
Predicted line-ups:
Man Utd XI [4-3-3]: De Gea, Young, Smalling, Lindelof, Shaw; Matic, McTominay, Pogba; Lingard, Rashford, Lukaku
Man City XI [4-3-3]: Ederson; Walker, Stones, Laporte, Zinchenko; Fernandinho, Bernardo, Silva; Sterling, Aguero, Sane
