Manchester United are battling an injury crisis ahead of their crunch Premier League meeting with rivals Liverpool on Sunday.
Marcos Rojo was forced off at half-time in Wednesday's defeat to Valencia as Jose Mourinho's suffered another blow ahead a gruelling run of domestic fixtures.
Luke Shaw, Anthony Martial and Matteo Darmian missed the win over Fulham on Saturday, while Chris Smalling was forced off at Old Trafford and all four were absent on Wednesday.
Diogo Dalot and Scott McTominay have suffered training injuries; Victor Lindelof and Alexis Sanchez remain sidelined.
"Marcos Rojo no, because he's injured," Mourinho said when asked if starters at Valencia would keep their place.
"The rest are not injured, they belong to the squad. We have lots of players that were not here because they are injured. This is our squad, our players. They have a chance to play Sunday.
"[Chris] Smalling is injured, [Victor] Lindelof is injured, [Matteo] Darmian is injured, [Anthony] Martial is injured, [Diogo] Dalot is injured. The only two players I could bring and didn't were [David] De Gea and [Nemanja] Matic.
"You are the first ones to make the stats and how many minutes he [Matic] is playing and that he needs a rest. If he doesn't have a rest in a match [where] we have already qualified, he would play until he explodes.
"It was a normal option to leave him out and [with] David it's to give a match to [Sergio] Romero. Romero is such a good goalkeeper; I played him in the Europa League final a couple of years ago."
