Ole Gunnar Solskjaer may be forced to reshuffle his attack for Manchester United's Premier League return against Watford on Saturday after several players withdrew from international duty through injury.
There are questions over the fitness of Nemanja Matic, Romelu Lukaku, Luke Shaw and Anthony Martial after they pulled out of playing in internationals.
Marcus Rashford and Jesse Lingard, who went on a warm-weather training camp to Dubai, will be hoping to return, while Eric Bailly is a doubt and Victor Lindelof's partner gave birth over the international break.
Antonio Valencia played for Ecuador and should return to contention, but Alexis Sanchez is out with a knee issue. Ashley Young is available after serving a suspension against Wolves in the FA Cup.
Solskjaer will be taking charge of his first match as United's permanent manager after signing a three-year contract on Thursday.
Provisional squad: De Gea, Romero, Grant, Dalot, Valencia, Young, Darmian, Lindelof, Rojo, Bailly, Jones, Shaw, Smalling, Fred, Garner, Gomes, Matic, Herrera, Pogba, McTominay, Pereira, Mata, Chong, Lingard, Greenwood, Martial, Lukaku, Rashford.
Predicted line-up: De Gea, Dalot, Smalling, Lindelof, Young, Matic, Herrera, Pogba, Lukaku, Rashford, Lingard
