A man was found dead after being hit by a car while "lying in the road" in Aigburth.
Ullet Road, near to the junction with Aigburth Road, remains closed after the crash on Saturday night between a Seat Ibiza car and a pedestrian.
A 69-year-old man is believed to have been lying in the road when he was hit by a car at around 9.45pm. It is not known if he was killed when the car struck him or if he had died before the collision.
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The driver of the car stopped at the scene and is assisting the police.
A joint investigation into the man's death is being carried out by the Merseyside Police Investigation team and the Roads Policing Unit.
The man's family has been informed and are being supported by specialist Family Liaison Officers.
Ullet Road is expected to remain closed for some time whilst investigations and forensic examinations are carried out at the scene.
DI Ben Dyer, said: "An investigation is underway to find out what has happened.
"We believe the man who died was lying in the road when the incident happened.
"We are currently carrying out house-to-house inquiries in the area and looking at CCTV footage to establish what happened.
"The family of the deceased has been informed and is being supported by specialist Family Liaison Officers from our Roads Policing Unit at this sad time.
"A Home Office post mortem will be carried out later today to establish the cause of death.
"I would ask any drivers in the area who saw anything, or who may have dashcam footage which could help our inquiries, to come forward. Any footage, or information, could be vital in establishing exactly what has occurred."
He added: "Diversions have been put in place and motorists are being advised to avoid the area and find alternative routes.
"We realise that this will cause disruption and would like to thank local residents and motorists for their patience and understanding whilst investigations are carried out."
Anyone who witnessed the collision, or has any CCTV or dashcam footage, is asked to contact @MerPolCC, the Roads Policing Unit on 0151 777 5747, 101 quoting reference 1110 of 25 September, or call Crimestoppers, anonymously on 0800 555 111.
Witness and CCTV enquiries are ongoing.
