How Manchester City cope without Sergio Aguero could determine whether their Premier League title defence goes beyond Christmas.
In the Argentine’s absence, Pep Guardiola’s side produced one of their flattest attacking performances in recent memory against Shakhtar Donetsk.
A 1-1 draw secured qualification to the knockout stages of the Champions League, but the lack of Aguero’s cutting edge was felt.
Gabriel Jesus is set to deputise for City’s all-time record scorer against Newcastle on Saturday as the champions attempt to stay within sight of leaders Liverpool.
Aguero’s thigh injury is expected to keep him out for three weeks, which means he will also miss the Manchester derby on December 7.
Guardiola has no other fresh injuries to contend with, but will recognise the need to add freshness to his squad.
Both Rodri and David Silva have complained of cramp in recent weeks, while Raheem Sterling has been quiet since returning from the last international break.
There could be returns for Kyle Walker. John Stones and Benjamin Mendy, who all sat out the game against Shakhtar.
Predicted Man City XI (4-3-3): Ederson; Walker, Stones, Fernandinho, Mendy; De Bruyne, Gundogan, Silva; Mahrez, Jesus, Sterling.
