They can do it on a warm, sunny afternoon in East London - boy can they do it on a warm, sunny afternoon in East London - but can Pep Guardiola's champions do it on a wet Saturday tea-time in Manchester against the Champions League finalists?
Probably.
But we'll find out for sure when Spurs visit this weekend. If you're having a punt make sure you read our betting preview from the man who knows City inside out, Stuart Brennan.
Win, lose or draw?
City to win another thriller 3-2. That's a whopping 22/1 with thepools.com
Who's a good bet for 1st scorer?
Kevin De Bruyne has started to move up through the gears, and in big games he tends to conjure something special. He's a special price, too, with thepools.com - 8/1 first scorer and 12/5 any time .
Who's on the naughty step? (first card)
City need to cope with Spurs' counters, and that means Aymeric Laporte's lack of pace could be exposed, with yellow to follow. Over four cards to be shown by Michael Oliver (two on Friday night for Liverpool v Norwich) is 5/4 .
Who's on pens?
If Aguero plays, it will be a wrestling match between him and Sterling. Aguero wins. He's 11/4 first scorer while Raheem Sterling is 7/2
Will City keep a clean sheet?
Unlikely. Spurs are always likely to score, and City's understaffed defence will face a serious test. Both teams to score is a solid 3/4 with thepools.com