The last thing Southampton needed after their humiliating 9-0 home defeat to Leicester City was a midweek trip to face the Premier League champions - but that's exactly what they've got.
The Saints suffered their worst ever defeat on Friday night, capitulating against Leicester as the Foxes ran riot with nine goals at St Mary's.
Ralph Hasenhuttl will be keen to forget that match completely, but it doesn't get any easier as the Saints travel to Manchester to face Man City in the Carabao Cup round-of-16 on Tuesday.
Pep Guardiola may have defensive problems, but the cup holders have plenty of talent in reserve with big names all vying for valuable minutes.
Carabao Cup preview
Manchester City vs Southampton
Venue: Etihad Stadium
Kick-off time: 7:45pm, Tuesday October 29
Man City team news and injuries
Fernandinho's late red card in Saturday's win over Aston Villa leaves Guardiola short at centre-back, with Aymeric Laporte and Rodri also out.
Oleksandr Zinchenko and Leroy Sane are also out for the hosts.
Man City predicted lineup (4-3-3): Bravo, Walker, Otamendi, Garcia, Angelino, De Bruyne, Gundogan, Foden, David Silva, Mahrez, Aguero
Tickets
For Man City ticket information, visit the club's website here.
Head to Head record (H2H)
Man City edge this fixture with 31 wins to Southampton's 31, and 25 draws.
City have won the last five meetings though, thrashing the Saints 6-1 in the League at home last November and following that up with a 3-1 away win in December.
Betting tips and odds
Match odds
- Man City to qualify: 1/10
- Southampton to qualify: 25/1
Correct score
| Scoreline | Man City win | Southampton win | Draw |
| 1-0 | 9/1 | 70/1 | 0-0 (33/1) |
| 2-0 | 6/1 | 125/1 | 1-1 (14/1) |
| 2-1 | 9/1 | 60/1 | 2-2 (25/1) |
| 3-0 | 11/2 | 200/1 |
Odds provided by Betfair. Click here to place a bet. Odds correct as of 5pm BST on Monday, October 28.
Prediction: Man City 3-0 Southampton
Those expecting Man City to beat Southampton by double figures will not have factored mentality into their prediction.
The Saints squad will be desperate to make amends for last Friday, and while a defeat is likely, Hasenhuttl will want his players fighting for every ball.
Live stream details and TV channel information
The match will not be televised live in the UK.
You can follow the action with Standard Sport's dedicated LIVE Carabao Cup blog.