So a staggering 163 days since a famous win in the Bernabeu, Manchester City get the chance to finish the job - after another short break.
It's more than a fortnight since City put five goals past Norwich City, which was five days after they plundered four at Watford.
But it's been almost three weeks since Champions League rivals Real Madrid last kicked a ball in anger - when they drew 2-2 with Leganes having already clinched La Liga title.
Will the lay-off affect either side's rhythm or momentum?
We won't have to wait long to find out.
City are odds on 4/6 favourites to win at the Etihad with thepools.com, with the draw and a Real Madrid victory both 10/3.
But trailing 2-1 from March's first leg Real need to score and will attack, which means both teams to score is another short price with thepools.com at 1/2.
However ... Real shipped goals in each of their last three matches, City showed their superiority in Spain last March so a City win and Both Teams To Score is a stand-out 9/5 with thepools.com.
That likelihood of goals makes thepools.com's special offer of Bet £10, and if both teams score get a £5 bonus, very appealing.
There are other Pools offers for tonight.
Last time out in Spain there were three yellow cards and a red for Sergio Ramos, so even with nailed on yellow card merchant Ramos suspended, BTTS and 5 or more bookings is another attractive offer at 6/4 with thepools.com.
While all new customers get a £6 Free Bet, no deposit, no strings attached! Sign up here:
Top tip
Man City win and Both Teams To Score: 9/5
