It's Man City-Saints part two - with Pep Gaurdiola's men a comfortable 3-1 up from the midweek Carabao Cup clash.
Will they pile even more pain on Southampton this weekend?
We asked the MEN's Manchester City write Simon Bajkowski for his verdict.
Win, lose or draw?
City to win. But you've got to put £12 on just to win a pound. If you fancy a 1/12 sure thing, bet here .
Who's a good bet for first scorer?
Raheem Sterling. It's daft to bet against him these days. But 3/1 first scorer with thepools.com is generous. Any time is 6/10 .
Who's on the naughty step?
Fernandinho. Almost guaranteed to play and just as likely to be in the thick of stopping attacks.
Who's on pens?
Aguero. Two goals in midweek against the same opposition, neither from the spot. He's 11/5 to score first this weekend and 4/9 any time .
Will City keep a clean sheet?
They conceded in midweek to the same opponents so you would back them to tighten up for Saturday. BTTS 'No' is 8/15 .
