Kyle Walker and Gabriel Jesus have tested positive for Covid-19, Manchester City have confirmed.
The club also confirmed that two members of staff have returned positive tests, and all four will now self-isolate for at least ten days.
That rules Walker and Jesus out for the Christmas fixtures against Newcastle, Everton and likely the trip to Chelsea in the new year. City then face Manchester United in the Carabao Cup semi-final in 12 days time on January 6.
A City statement said: "Manchester City FC can confirm that Gabriel Jesus, Kyle Walker, and two members of staff have tested positive for COVID-19.
"All four personnel will now observe a period of self-isolation in accordance with Premier League and UK Government protocol on quarantine.
"Everyone at the Club wishes our colleagues a speedy recovery over the Christmas period ahead of their return to work, training and competition."
