Ireland's incidence rate now stands at 209.6 after a Christmas surge that has seen 9,979 new Covid-19 cases in just 14 days.
Dr Tony Holohan has warned that the situation is fast deteriorating and with lockdown back underway, it will be a week or two into January before restrictions have an impact on cases.
Donegal, Wexford, Limerick and Louth now all have rates of more than 300 per 100,000 over the past 14-days.
Speaking on Sunday night, Dr Holohan said: "If we do not act now to stop the spread of COVID-19, we will not be able to protect those in our society that are most at risk of serious illness or death.
"Stay home, do not visit friends or family unless you are providing essential care and do not have visitors to your home. Follow the public health advice."
Here's an in-depth look at how each county in the Republic of Ireland is faring right now - data is from the Department of Health up until midnight, December 26.
County-by-county Covid-19 situation
Donegal
14-day incidence rate: 425.9
Cases in the last 14 days: 678
Worst hit local area: Carndonagh
Wexford
14-day incidence rate: 348.6
Cases in the last 14 days: 522
Worst hit local area: New Ross
Limerick
14-day incidence rate: 334.5
Cases in the last 14 days: 652
Worst hit local area: Adare-rathkeale
Louth
14-day incidence rate: 305.7
Cases in the last 14 days: 394
Worst hit local area: Drogheda (urban)
Monaghan
14-day incidence rate: 288.3
Cases in the last 14 days: 177
Worst hit local area: Ballybay-clones
Kilkenny
14-day incidence rate: 268.1
Cases in the last 14 days: 266
Worst hit local area: Castlecomer
Kerry
14-day incidence rate: 249.1
Cases in the last 14 days: 368
Worst hit local area: Kenmare
Dublin
14-day incidence rate: 249.1
Cases in the last 14 days: 3,356
Worst hit local area: Ongar
Carlow
14-day incidence rate: 224.8
Cases in the last 14 days: 128
Worst hit local area: Muinebeag
Cavan
14-day incidence rate: 195.6
Cases in the last 14 days: 149
Worst hit local area: Bailieborough - Cootehill
Sligo
14-day incidence rate: 192.3
Cases in the last 14 days: 126
Worst hit local area: Sligo-drumcliff
Laois
14-day incidence rate: 190.1
Cases in the last 14 days: 161
Worst hit local area: Portlaoise
Meath
14-day incidence rate: 176.4
Cases in the last 14 days: 344
Worst hit local area: Laytown - Bettystown
Kildare
14-day incidence rate: 168.5
Cases in the last 14 days: 375
Worst hit local area: Naas
Cork
14-day incidence rate: 162.5
Cases in the last 14 days: 882
Worst hit local area: Cork City South East
Waterford
14-day incidence rate: 160.1
Cases in the last 14 days: 186
Worst hit local area: Waterford City
Mayo
14-day incidence rate: 129.5
Cases in the last 14 days: 169
Worst hit local area: Claremorris
Galway
14-day incidence rate: 123.2
Cases in the last 14 days: 318
Worst hit local area: Galway City East
Clare
14-day incidence rate: 115.3
Cases in the last 14 days: 137
Worst hit local area: Shannon
Westmeath
14-day incidence rate: 113.8
Cases in the last 14 days: 101
Worst hit local area: Moate
Wicklow
14-day incidence rate: 112.3
Cases in the last 14 days: 160
Worst hit local area: Wicklow LEA
Tipperary
14-day incidence rate: 94.0
Cases in the last 14 days: 150
Worst hit local area: Carrick-on-suir
Roscommon
14-day incidence rate: 88.3
Cases in the last 14 days: 47
Worst hit local area: Boyle
Longford
14-day incidence rate: 88.1
Cases in the last 14 days: 36
Worst hit local area: Longford town
Offaly
14-day incidence rate: 83.4
Cases in the last 14 days: 65
Worst hit local area: Edenderry
Leitrim
14-day incidence rate: 68.7
Cases in the last 14 days: 22
Worst hit local area: Carrick-on-shannon
