Liverpool bring back the big guns as they look to finish the job against RB Leipzig and reach the Champions League quarter-finals.
Jurgen Klopp made seven changes from the home loss to Chelsea and the home loss to Fulham, the most between Premier League games during the manager's entire tenure.
Three of the back four from Thursday's defeat against Chelsea were switched with Neco Williams, Rhys Williams and Nat Phillips all coming in for the record-setting six consecutive home defeat.
In midfield, James Milner and Naby Keita started in place of Thiago and Curtis Jones, while Diogo Jota made his first start since December with Xherdan Shaqiri also up front as they replaced Sadio Mane and the injured Roberto Firmino.
Firmino is out but Mane and Mo Salah to return in attack along with a start for Diogo Jota.
Fabinho has been restored to midfield to add control higher up the pitch - but that could put pressure on the defence.
Liverpool vs RB Leipzig lineups
Liverpool XI: Alisson, Alexander-Arnold, Phillips, Kabak, Robertson, Thiago, Fabinho, Wijnaldum, Mane, Salah, Jota
Subs: Milner, Keita, Adrian, Oxlade-Chamberlain, Jones, Tsimikas, Shaqiri, Origi, Ben Davies, Rhys Williams, Neco Williams, Harvey Davies
RB Leipzig XI: Gulacsi, Mukiele, Upamecano, Klostermann, Kampl, Adams, Olmo, Sabitzer, Nkunku, Poulsen, Forsberg
Subs: Orban, Konate, Haidara, Hwang, Sorloth, Samardzic, Kluivert, Halstenberg, Martinez, Henrichs
Injury list: Van Dijk, Gomez, Matip, Kabak, Henderson, Kelleher, Firmino
