Tottenham are without key central midfielders as they visit Premier League leaders Liverpool in this weekend's standout fixture.
Both Eric Dier (hip) and Harry Winks (groin) have returned from the international break nursing injuries, while Serge Aurier (hamstring) will be assessed.
It's a double blow for Mauricio Pochettino, leaving his central midfield options very limited. Moussa Sissoko and Victor Wanyama will likely vie for a place in a five-man midfielder alongside Dele Alli and Christian Eriksen.
For Liverpool, Trent Alexander-Arnold (back), Naby Keita (knock) and Xherdan Shaqiri (groin) are hopeful of a return to the squad. Joe Gomez (ankle) and Alex Oxlade-Chamberlain (thigh) remain a couple of weeks away.
Jurgen Klopp said at his pre-match press conference on Friday: "I think it's the first time everybody came back [from international duty] healthy!"
The right-back is only hopeful of playing from the off, with Gigi Wijnaldum, Fabinho and James Milner expected to start at Anfield.
Liverpool vs Tottenham line-ups: Predicted XIs
Liverpool XI (4-3-3): Alisson; Alexander-Arnold, Matip, Van Dijk, Robertson; Wijnaldum, Fabinho, Milner; Salah, Mane, Firmino
Tottenham (3-5-2): Lloris; Alderweireld, Sanchez, Vertonghen; Trippier, Sissoko, Eriksen, Dele, Rose; Son, Kane