Premier League heavyweights Liverpool and Manchester City look set to lock horns with Anfield as the battlefield.
Bookies Grosvenor Sport have put Man City as the slight favourites at 6/4 while Liverpool are 37/20 and a draw 49/20.
The Inside Track's Tom Phillips is backing Mo Salah to be the standout player in what could be an end-to-end match.
Both sides will be eager to get one over the other in order to gain an early advantage in the title race but the two clubs go into this weekend with contrasting results in the Champions League.
Liverpool continue their fine record against Porto with an impressive 5-1 victory at the Estadio do Dragao while Man City suffered a 2-0 defeat with Lionel Messi stealing the headlines in Paris.
It is a situation far from ideal for Pep Guardiola but he has admitted recently his rivalry with Jurgen Klopp has made him a better manager so it will be interesting how this match unfolds at Anfield.
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Team stats
Liverpool have not lost consecutive league games against City since a run of four which ended in 1937.
The Reds are the only side still unbeaten in the Premier League this season while Klopp's side have netted more goals than any other side this season.
However, City have the best defence record conceding just one goal and keeping a clean sheet in their last five league matches.
Player to watch
Mo Salah will be the main man for Liverpool after an impressive start to the season.
The Egyptian winger has picked up eight goals in as many matches in all competitions.
H2H
This will be the 188th meeting between the two sides with Liverpool having the better overall record with 90 wins, 49 draws and 48 defeats.
However, the Reds have only picked up one win in their last seven meetings in all competitions against Guardiola's side.
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